Selected Publications

Dölen G. and Wilkinson MThe Emerging Neurobiology of Psychedelics: Critical Periods, Metaplasticity, and Extracellular Matrix Remodeling. Annual Review of Neuroscience, 49th Edition (2026). https://doi.org/10.1146/annurev-neuro-112723-045129 PDF


François M., Vranich KL., Delgado IC., Lafond A., Natalie R Lopatinsky N.R., Davis T., Lewis E.M., Kuromaru M., Hassouna R., Williams B., Ho S.E., Souza L.A.C., Neri D., Oh Y., Makinson CD, Bath K.G., Dölen G., Zeltser L.M. Amygdala AVPR1A mediates susceptibility to chronic social isolation in females. Nature Communications. Nov 4;16(1):9740. doi: 10.1038/s41467-025-64742-y. PMID: 41188217 PDF


Baden T, Briseño J, Coffing G, Cohen-Bodénès S, Courtney A, Dickerson D, Dölen G, Fiorito G, Gestal C, Gustafson T, Heath-Heckman E, Hua Q, Imperadore P, Kimbara R, Król M, Lajbner Z, Lichilín N, Macchi F, McCoy MJ, Nishiguchi MK, Nyholm SV, Otjacques E, Pérez-Ferrer PA, Ponte G, Pungor JR, Rogers TF, Rosenthal JJC, Rouressol L, Rubas N, Sanchez G, Santos CP, Schultz DT, Seuntjens E, Songco-Casey JO, Stewart IE, Styfhals R, Tuanapaya S, Vijayan N, Weissenbacher A, Zifcakova L, Schulz G, Weertman W, Simakov O, Albertin C. Cephalopod-omics: Emerging Fields and Technologies in Cephalopod Biology. Integrative and Comparative Biology. 2023 Jun 27:icad087. doi: 10.1093/icb/icad087. PMID: 37370232 PDF



Nardou R., Sawyer E.,  Song Y.J., Wilkinson M., Padovan-Hernandez Y.,  de Deus J.L., Wright N., Lama C., Faltin S., Goff L.A., Stein-O’Brien G.L., and Dölen G. Psychedelics reopen the critical period for social reward learning. Nature 2023. DOI: 10.1038/s41586-023-06204-3 PDF


 Hayes LN, An K, Carloni E, Li F, Vincent E, Trippaers C, Paranjpe M, Dölen G , Goff LA, Ramos A, Kano S, Sawa A. Prenatal immune stress blunts microglia reactivity, impairing neurocircuitry. Nature 2022. DOI: https://doi.org/10.1038/s41586-022-05274-z . PDF


Grearson A, Dugan A, Sakmar T, Sivitilli, DM, Gire DH, Caldwell RL, Niell CM, Dölen G, Wang ZY, Grasse B. The lesser Pacific striped octopus, Octopus chierchiae: an emerging laboratory model for the study of octopuses. Frontiers in Marine Science 2021. DOI: 10.3389/fmars.2021.753483 PDF


Lewis E.M, Stein-O'Brien G.L., Patino A.V., Nardou R., Grossman C.D., Brown M., Bangamwabo B., Ndiaye N., Giovinazzo D., Dardani I., Jiang C., Goff L.A., & Dölen G. Parallel Social Information Processing CircuitsAre Differentially Impacted in Autism. Neuron. 2020 (in press). doi: 10.1016/j.neuron.2020.10.002. Epub 2020 Oct 27,2020. PMID: 33113347 PDF


Nardou R, Lewis EM, Rothhaas R, Xu R, Yang A, Boyden E, & Dölen G. Oxytocin-dependent reopening of a social reward learning critical period with MDMA. Nature. 2019 May;569(7754):116-120. doi: 10.1038/s41586-019-1075-9. Epub 2019 Apr 3. PMID: 30944474   PDF


Edsinger, E and Dölen G. A conserved role for serotonergic neurotransmission in mediating social behavior in octopus. Current Biology. 2018 October 8; 28: 1–7. PMID: 30245101  PDF


Dölen G. Mindreading emerged at least twice in the course of evolution. In Linden, D.J., ed. Think Tank: Forty Curious Neuroscientists Explain the Biological Roots of Human Experience. Yale University Press  (April 2018). ISBN: 9780300225549 . Library (Worldcat.org)  Amazon. PDF


 Hung LW, Neuner S, Polepalli JS, Beier K, Wright M, Walsh J, Lewis E, Luo L, Deisseroth K , Dölen G , Malenka, RC. Gating of social reward by oxytocin in the ventral tegmental area. Science . 2017 Sep 29;357(6358):1406-1411.  PMID: 28963257PDF


Dölen G,  Setting the mood for love. Nature Neuroscience . 2017 Feb 23;20(3):379-380. PMID: 28230842 PDF 


Dölen G,  and Sahin M Editorial: Essential Pathways and Circuits of Autism Pathogenesis.2016 Apr 26;10:182.  Frontiers in Neuroscience. PMCID: PMC4844597  PDF


Lammel S,Dölen G, and Malenka RC. Optogenetic Approaches to Neural Circuit Analysis in the Mammalian Brain. In Lehner T, Miller BL, and State MW, eds.  Genomics, Circuits, and Pathways in Clinical Neuropsychiatry. Elsevier, Inc. 2016. ISBN: 9780128001059


Dölen G,  Autism: oxytocin, serotonin, and social reward. Social  Neuroscience. 2015 Aug 28.  PMID: 26317636 PDF


Dölen G, Malenka RC, Perlumutter JS, Brose N, Frackowiak R, Cuthbert BN, Diester I, Mansuy I, Kroker, KS, Boekers TM, Pascual-Leone A, Feng G. Pathophysiological Toolkit: Genes to Circuits. In Nikolich, K. and S. E. Hyman, eds. Translational Neuroscience: Toward New Therapies. Strüngmann Forum Reports, vol. 17, J. Lupp, series editor. Cambridge, MA: MIT Press, 2015. ISBN: 9780262029865. PDF


Diester I, Hefti F, Mansuy I, Pascual-Leone A, Robbins TW, Rubin LL, Sawa A, Wernig M, Dölen G, Hyman SE, Mucke L, Nikolich K, and Sommer B. Bridging the Gap between Patients and Models. In Nikolich, K. and S. E. Hyman, eds. Translational Neuroscience: Toward New Therapies. Strüngmann Forum Reports, vol. 17, J. Lupp, series editor. Cambridge, MA: MIT Press, 2015. ISBN: 9780262029865. PDF


Dölen G.Oxytocin: parallel processing in the social brain?Journal of Neuroendocrinology. 2015 Jun;27(6):516-35.PMID: 25912257 PDF


Dölen G . SFARI: Cross Talk.https://spectrumnews.org/opinion/cross-talk/cross-talk-how-do-we-fix-the-broken-postdoc-pipeline/  PDF


Dölen G , Malenka RC. The emerging role of nucleus accumbens oxytocin in social cognition. Biological Psychiatry . 2014 Sep 1;76(5):354-5. PMID: 25103539 PDF


Dölen G , Darvishzadeh A, Huang KW, Malenka, RC. Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin.  Nature 2013 Sep 12;501(7466):179-84. PMID: 24025838 PDF



Portmann T, Yang M, Mao R, Panagiotakos G, Ellegood J, Dölen G , Bader PL, Grueter BA, Goold C, Fisher E, Clifford K, Rengarajan P, Kalikhman D, Loureiro D, Saw NL, Zhengqui Z, Miller MA, Lerch JP, Henkelman RM, Shamloo M, Malenka RC, Crawley JN, and Dolmetsch RE. Behavioral Abnormalities and Circuit Defects in the Basal Ganglia of a Mouse Model of 16p11.2 Deletion Syndrome. Cell Rep. 2014 May 22;7(4):1077-92. PMID: 24794428 PDF


Bhakar AL, Dölen G , Bear MF. The pathophysiology of fragile X (and what it teaches us about synapses). Annu Rev Neurosci.  2012;35:417-43. PMID: 22483044 PDF


Dölen G , Carpenter RL, Ocain TD, Bear MF. Mechanism-based approaches to trating fragile X. Pharmacol Ther. 2010 Jul;127(1):78-93. PMID: 20303363 PDF


Dölen G , Bear MF. Fragile X syndrome and autism: from disease model to therapeutic targets. J Neurodev Disord. 2009 Jun;1(2):133-40 PMID: 21547712 PDF


Dölen G , Bear MF. Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome. J Physiol. 2008 Mar 15;586(6):1503-8. PMID: 18202092 PDF


Bear MF, Dölen G , Osterweil E, Nagarajan N. Fragile X: translation in action. Neuropsychopharmacology . 2008 Jan;33(1):84-7. PMID: 17940551 PDF


Dölen G . Genetic interaction between Fmr1 and Grm5: A role for mGluR5 in the pathogenesis of Fragile X Syndrome. (2008). Thesis-Ph.D.-- Brown University. PDF


Dölen G , Osterweil E, Rao BS, Smith GB, Auerbach BD, Chattarji S, Bear MF. Correction of fragile X syndrome in mice. Neuron . 2007 Dec 20;56(6):955-62. PMID: 18093519 PDF


Dölen G , Bear MF. Courting a cure for fragile X. Neuron . 2005 Mar 3;45(5):642-4. PMID: 15748838 PDF


Herrera E, Brown L, Aruga J, Rachel RA, Dölen G , Mikoshiba K, Brown S, Mason CA. Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell. 2003 Sep 5;114(5):545-57. PMID: 13678579 PDF


Rachel RA, Dölen G , Hayes NL, Lu A, Erskine L, Nowakowski RS, Mason CA. Spatiotemporal features of early neuronogenesis differ in wild-type and albino mouse retina. J Neurosci. 2002 Jun 1;22(11):4249-63. PMID: 12040030 PDF


Dölen, G . The Development of mind: perspectives from Autistic disorder. (1997). Unpublished coursework- A.B.-- Duke University. PDF